Lorenzo's work is included in many impressive private collections throughout the world, which has lead to a prodigious amount of commissioned work. This includes being commissioned by the Vatican to sculpt the likeness of Saint Anthony, in commemoration of the Eighth Centennial of the Saint's birth. Lorenzo's sculpture was blessed by the Holy Father in Saint Peter's Square before it was placed in the Basilica del Santo in Padua in 1995. He has also been commissioned by the United Nations to produce a stamp for their collection, as well as placing several monumental sculptures throughout the UK and Europe.

His ongoing project, 'The Globe Of Life' which represents the hundred most important moments in history, looks set to be his most significant work to date, with five monumental bronze sculptures linking each continent. Other than having exhibited throughout the United States, Lorenzo has shown his work in South America, Europe and Asia. In April 2003, Lorenzo's monumental sculpture, 'Encounters', which has been commissioned by Fundatur and donated to the city of Mallorca, was unveiled opposite the Museum of Modern Art in Palma de Mallorca. The artist has continued to undertake both private and public commissions internationally.

Many of Lorenzo's sculptures often featured the symbol that has become synonymous with Lorenzo’s work – the human hand. “The reason I sculpt the hand is because I need to communicate in a universal language, especially since I exhibit in five continents. The use of this hand language helps me achieve this, creating a dialogue rather than a monologue,” he explains. “The hand holds so much power – the power to love, to hate, to create, to destroy. I have injected a lifetime of experience into Evolution – it is about my past, present and future.” Commenting on his work, Lorenzo says, “It is the viewer that interests me, not the art critic...I make art for myself and the people who wish to come along for a ride through my dreams.”