Troels Wörsel is self-taught and since the 1970s has exhibited both in Denmark and abroad. This was also when he moved to Munich and later Cologne. In Munich he was affiliated with the Academy and worked in a studio supplied by the BASF concern. In those years he was heavily influenced by the German art scene which was the rallying ground for ambitious, international artists. Since 1997 Wörsel has lived and worked in Pietrasanta in Italy.

In the 1970s he was interested mostly in Pop art and conceptual art. Moreover philosophical issues such as the relationship between space and time characterised his art.

In the early 1980s the purely painterly caught his interest more than the idea behind the work. He experimented with the wild painting and contributed to the pioneer exhibition Rundschau Deutschland and Bildwechsel at West Berlin's Akademie der Künste.

Since 1969 Wörsel has participated in a large number of exhibitions: Biennale de Paris (1975), Fyns Stifts Kunstmuseum (1979), Städtisches Kunstmuseum Bonn (1982), Visual Arts Museum in New York (1983), Malmö Konsthall (1987), Nordiskt Konstcentrum in Helsinki (1989), Kunsthallen Brandts Klædefabrik in Odense (1992, 1996), Kunstmuseet Trapholt in Kolding (1994), Musée des Beaux-Art de Nantes (1996), Sønderjyllands Kunstmuseum in Tønder (2000), Reykjavik Art Museum (2002), Victoria Miro in London (2002), Kunstforeningen GL Strand in Copenhagen, Sophienholm in Lyngby (2004), Nordiska Akvarellmuseet in Skärhamn (2006) and the 52. Venice Biennal (2007).